Never-smokers’ lung cancers are genetically different from smokers’ tumors, study shows

Researchers have identified unique genetic signatures of lung cancer in people who never smoked cigarettes, using whole genome sequencing to analyze tumors from this under-studied population.

The new study, published Monday in Nature Genetics, more than doubles the number of sequenced lung tumors from never-smokers and helps point the way toward developing personalized treatments distinct from those used for smokers’ cancers, the authors said.

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