Population-based risk compensation may have been a driving force in UK’s COVID pandemic

The COVID-19 pandemic has irreversibly altered our lives in many ways. However, available COVID vaccines are effective against (symptomatic) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, hospitalizations, and even death. Despite a diminishing protective effect against infection and onward transmission after vaccination, and a slightly diminished effect with the Delta variant compared to the Alpha variant, protection against severe outcomes remains high.